The FDA approved BOTOX® Cosmetic in 2002 for the treatment of moderate to severe Glabellar Lines in patients 18 to 65 years of age. Botox ® and Dysport are injectables made from Botulinum A toxin and designed to help eliminate or improve persistent facial wrinkles. This non-surgical procedure commonly treats areas like frown lines between the eyebrows (Glabellar frown complex), “crow’s feet” and creases on the forehead.
Length of treatment:
About 10 to 15 minutes.
Although rare, side effects may include temporary bruising, headache, respiratory infection, droopy eyelids and nausea. Facial pain, redness at the injection site and muscle weakness are less frequent reactions. Patients with neuromuscular disorders such as ALS, Myasthenia Gravis, or Lambert-Eaton syndrome may be at increased risk of serious adverse events and should have this procedure. There is also a small risk of allergic reaction.
Immediate — no down time.
The effects of Botox ® injections will appear within 3-7 days, and may last up to 3-4 months.
BOTOX® (botulinum toxin type A) is a 150 kD molecule (100 kD heavy chain and 50 kD light chain) that binds to the presynaptic nerve membrane and blocks the release of acetylcholine. Once internalized into the nerve cell, the chains dissociate and the light chain catalyzes cleavage of SNARE proteins in the synaptic fusion complex. Studies have shown Botox ® to relieve migraine headaches, excessive sweating, uncontrollable blinking and muscle spasms in the neck and eye. It is also used to help treat overactive bladders, control pain during operations, help children with cerebral palsy, prevent ringing in the ears, assist diabetics with weight gain and control drooling in some cerebral palsy patients.